DUF may refer to:
Duffy (born 23 June 1984 as Amie Ann Duffy) is a Welsh singer, songwriter and actress. Born in Gwynedd, Wales, she was introduced to Jeannette Lee of Rough Trade Records, which led to her signing a recording contract with A&M Records in 2007.
Michael Andrew "Duff" McKagan (born February 5, 1964) is an American musician, singer, songwriter and author.
Duffy antigen/chemokine receptor (DARC), also known as Fy glycoprotein (FY) or CD234 (Cluster of Differentiation 234), is a protein that in humans is encoded by the DARC gene.
Duff Beer is a brand of beer that originally started as a fictional beverage on the animated series The Simpsons.
The Dufourspitze is the highest peak of Monte Rosa, a huge ice-covered mountain massif in the Alps. Dufourspitze is the highest mountain peak of both Switzerland and the Pennine Alps and is also the second-highest mountain of the Alps and Europe outside the Caucasus.
Welsh singer and songwriter Duffy has released two studio albums, six extended plays (under the name of Duffy) and one extended play (under the name of Aimée Duffy), six singles and seven music videos.
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Alfred Duff Cooper, 1st Viscount Norwich, GCMG, DSO, PC (22 February 1890 – 1 January 1954), known as Duff Cooper, was a British Conservative Party politician, diplomat and author.
Matt Duffer and Ross Duffer (born February 1984), known professionally as the Duffer Brothers, are American twin brothers who write and direct science fiction films, horror films and television shows.