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Vqmr srna

The meaning of «vqmr srna»

VqmR small RNA was discovered in Vibrio cholerae, a bacterium which can cause cholera, using differential RNA sequencing (sRNA-seq) under conditions of low and high cell density which were being used to study quorum sensing (QS).[1] QS controls virulence and biofilm formation in Vibrio cholerae; it has been shown previously that it is directed by the Qrr sRNAs.[2][3] VqmR has been shown to repress the expression of multiple mRNAs including the rtx (repeats in toxin) toxin genes and the vpsT , which is required for biofilm formation. In fact, VqmR which is highly conserved in vibrionaceae, was shown to strongly inhibit biofilm formation by repressing the vpsT gene; it could be the link between biofilm formation and QS.[1]

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