Afa or AFA may refer to:
Arthur "Afa" Anoaʻi Sr. (born November 21, 1942) is a Samoan American retired professional wrestler and professional wrestling manager.
Afa Anoaʻi Jr. (born October 6, 1984) is an American professional wrestler. He is best known for his appearances with the professional wrestling promotion WWE in the mid-2000s under the ring name Manu.
Afa (or Afà in Corsican) is a French commune in the Corse-du-Sud department of France on the island of Corsica.
Afanasy Afanasyevich Fet (Russian: Афана́сий Афана́сьевич Фет; IPA: [ɐfɐˈnasʲɪj ɐfɐˈnasʲjɪvʲɪtɕ ˈfʲɛt]), later known as Shenshin (Russian: Шенши́н; IPA: [ʂɨnˈʂɨn]); 5 December [O.S.
The Afar (Afar: Qafár), also known as the Danakil, Adali and Odali, are an ethnic group inhabiting the Horn of Africa.
The Afar Regional State (Afar: Qafar; Amharic: አፋር ክልል?) is one of the nine regional states (kililoch) of Ethiopia, and is the homeland of the Afar people.
Afamelanotide (melanotan I, CUV1647; brand name Scenesse) is a synthetic peptide and analogue of α-melanocyte stimulating hormone used to prevent skin damage from the sun in people with erythropoietic protoporphyria in Europe since January 2015. It is administered as an implant that is placed under the skin; the implant lasts for two months.