AFC is an abbreviation that may refer to:
Amsterdamsche Football Club Ajax (Dutch pronunciation: [ˈaːjɑks]), also AFC Ajax, Ajax Amsterdam or simply Ajax, is a Dutch professional football club based in Amsterdam.
A.F.C. Rushden & Diamonds is an English football club based in Northamptonshire. They played their opening season at Kiln Park, the home of Raunds Town, in 2011–12 and have subsequently shared the Dog & Duck ground with Wellingborough Town since July 2012. The club was formed in July 2011 by supporters after Rushden & Diamonds, a former Football League club, were expelled from the Football Conference and liquidated.
Athletic Football Club Eskilstuna, also known simply as AFC Eskilstuna, is a Swedish football club located in Eskilstuna.
This page details statistics of the AFC Futsal Club Championship
The American Football Conference North Division, or AFC North, is a division of the National Football League's (NFL) American Football Conference (AFC).