CPB may refer to:
CPBL Home Run Derby is generally held before the day of the CPBL All-Star Game.
CPB Bank was the Greek branch of Cyprus Popular Bank. The bank was founded under the name Marfin Egnatia Bank.
The Annenberg Foundation is a family foundation that provides funding and support to non-profit organizations in the United States and around the world.
The Communist Party of Ukraine (Ukrainian: Комуністична Партія України Komunistychna Partiya Ukrayiny, КПУ, KPU; Russian: Коммунистическая партия Украины), known as the Communist Party (Bolshevik) of Ukraine until 1952, was the Ukrainian branch of the Communist Party of the Soviet Union (CPSU).
CIMIC Group Limited (formerly known as Leighton Holdings prior to April 2015) is a leading international contractor.
Carboxypeptidase B2 (CPB2), also known as carboxypeptidase U (CPU), plasma carboxypeptidase B (pCPB) or thrombin-activatable fibrinolysis inhibitor (TAFI), is an enzyme that, in humans, is encoded by the gene CPB2.