CVN may refer to:
In molecular biology, the CVNH domain (CyanoVirin-N Homology domain) is a conserved protein domain. It is found in the sugar-binding antiviral protein cyanovirin-N (CVN) as well as proteins from filamentous ascomycetes and in the fern Ceratopteris richardii.
USS Enterprise (CVN-65), formerly CVA(N)-65, is a decommissioned United States Navy aircraft carrier. She was the world's first nuclear-powered aircraft carrier and the eighth United States naval vessel to bear the name.