DEP may refer to:
Depleted uranium (DU; also referred to in the past as Q-metal, depletalloy or D-38) is uranium with a lower content of the fissile isotope U-235 than natural uranium.
A department store or magazine is a retail establishment offering a wide range of consumer goods in different product categories known as "departments".
Depression is a state of low mood and aversion to activity that can affect a person's thoughts, behavior, feelings, and sense of well-being.
Real Club Deportivo de La Coruña (Spanish pronunciation: [reˈal ˈkluβ ðepoɾˈtiβo ðe la koˈɾuɲa]; English: Royal Sporting Club of La Coruña) is a professional football club based in the city of A Coruña (known in Spanish as La Coruña), Galicia, Spain.
In the administrative divisions of France, the department (French: département, pronounced: [depaʁt(ə)mɑ̃]) is one of the three levels of government below the national level ("territorial collectivities"), between the administrative regions and the commune.
In optics, particularly as it relates to film and photography, depth of field (DOF), also called focus range or effective focus range, is the distance between the nearest and farthest objects in a scene that appear acceptably sharp in an image.
In accountancy, depreciation refers to two aspects of the same concept: