EP, ep, or Ep may refer to:
Epistemology ( (listen); from Greek, Modern ἐπιστήμη, epistēmē, meaning 'knowledge', and -logy) is the branch of philosophy concerned with the theory of knowledge.
The Episcopal Church (TEC) is a member church of the worldwide Anglican Communion based in the United States with dioceses elsewhere.
Epic Games, Inc. (formerly Potomac Computer Systems and later Epic MegaGames, Inc.) is an American video game and software development company based in Cary, North Carolina.
Epilepsy is a group of neurological disorders characterized by epileptic seizures. Epileptic seizures are episodes that can vary from brief and nearly undetectable periods to long periods of vigorous shaking.
Epigenetics is the study of heritable phenotype changes that do not involve alterations in the DNA sequence.
The Epstein–Barr virus (EBV), formally called Human gammaherpesvirus 4, is one of eight known human herpesvirus types in the herpes family, and is one of the most common viruses in humans.
The Epic of Gilgamesh () is an epic poem from ancient Mesopotamia that is often regarded as the earliest surviving great work of literature.
Ephedrine is a medication and stimulant. It is often used to prevent low blood pressure during spinal anesthesia.
Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in defined populations.