IS can refer to:
Israel (/ˈɪzreɪəl/; Hebrew: יִשְׂרָאֵל Yisrā'el; Arabic: إِسْرَائِيل Isrāʼīl), officially the State of Israel (Hebrew: מְדִינַת יִשְׂרָאֵל Medīnat Yisrā'el [mediˈnat jisʁaˈʔel]; Arabic: دَوْلَة إِسْرَائِيل Dawlat Isrāʼīl [dawlat ʔisraːˈʔiːl]), is a country in the Middle East, on the southeastern shore of the Mediterranean Sea and the northern shore of the Red Sea.
Islam (/ˈɪslɑːm/; Arabic: الإسلام, IPA: [alʔisˈlaːm]) is an Abrahamic monotheistic religion which professes that there is only one and incomparable God (Allah) and that Muhammad is the last messenger of God.
Istanbul (UK /ɪstænbʊl/ or US /-stɑːn-/; Turkish: İstanbul [isˈtɑnbuɫ]), historically known as Constantinople and Byzantium, is the most populous city in Turkey and the country's economic, cultural, and historic center.
The Isle of Man (/ˈmæn/; Manx: Mannin [ˈmanɪn] or Ellan Vannin [ˈɛlʲən ˈvanɪn]), also known simply as Mann, is a self-governing crown dependency in the Irish Sea between England and Northern Ireland.
Sir Isaac Newton PRS (/ˈnjuːtən/; 25 December 1642 – 20 March 1726/27) was an English mathematician, astronomer, and physicist (described in his own day as a "natural philosopher") who is widely recognised as one of the most influential scientists of all time and a key figure in the scientific revolution.
The Islamic, Muslim, or Hijri calendar (Arabic: التقويم الهجري at-taqwīm al-hijrī) is a lunar calendar consisting of 12 months in a year of 354 or 355 days.
The Israeli–Palestinian conflict (Hebrew: הסכסוך הישראלי-פלסטיני Ha'Sikhsukh Ha'Yisraeli-Falestini; Arabic: النزاع الفلسطيني - الإسرائيلي al-Niza'a al'Filastini al 'Israili) is the ongoing struggle between Israelis and Palestinians that began in the mid-20th century.