IS can refer to:
Israel (; Hebrew: יִשְׂרָאֵל, Arabic: إِسْرَائِيل), officially the State of Israel, is a country in the Middle East, on the southeastern shore of the Mediterranean Sea and the northern shore of the Red Sea.
Islam () is an Abrahamic monotheistic religion which professes that there is only one and incomparable God (Allah) and that Muhammad is the last messenger of God.
The Islamic State of Iraq and the Levant (ISIL, IPA: ), also known as the Islamic State of Iraq and Syria (ISIS ), Islamic State (IS), and by its Arabic language acronym Daesh (Arabic: داعش dāʿish, IPA: [ˈdaːʕɪʃ]), is an Arabic Salafi jihadist militant group and unrecognised proto-state that follows a fundamentalist, Wahhabi doctrine of Sunni Islam.
The Isle of Man (; Manx: Mannin [ˈmanɪn] or Ellan Vannin [ˈɛlʲən ˈvanɪn]), also known simply as Mann, is a self-governing crown dependency in the Irish Sea between the islands of Great Britain and Ireland.
Istanbul (UK: , or US: ; Turkish: İstanbul [isˈtɑnbuɫ]), historically known as Constantinople and Byzantium, is the most populous city in Turkey and the country's economic, cultural, and historic center.
Sir Isaac Newton PRS (; 25 December 1642 – 20 March 1726/27) was an English mathematician, astronomer, and physicist (described in his own day as a "natural philosopher") who is widely recognised as one of the most influential scientists of all time and a key figure in the scientific revolution.
The Isner–Mahut match at the 2010 Wimbledon Championships was a first round Men's Singles match, in which the American 23rd seed John Isner played French qualifier Nicolas Mahut.
ISO 8601 Data elements and interchange formats – Information interchange – Representation of dates and times is an international standard covering the exchange of date and time-related data.
The Israeli–Palestinian conflict (Hebrew: הסכסוך הישראלי-פלסטיני, translit. Ha'Sikhsukh Ha'Yisraeli-Falestini; Arabic: النزاع-الفلسطيني الإسرائيلي, translit.