KE, ke, and variations may refer to:
Kerala (/ˈkɛrələ/) historically known as Keralam, is an Indian state in South India on the Malabar Coast.
Kentucky (/kənˈtʌki/, kən-TUCK-ee), officially the Commonwealth of Kentucky, is a state located in the east south-central region of the United States.
Kenya (/ˈkɛnjə/; locally [ˈkɛɲa]), officially the Republic of Kenya, is a country in Africa and a founding member of the East African Community (EAC).
Ketamine, sold under the brand name Ketalar among others, is a medication mainly used for starting and maintaining anesthesia.