OF or Of may refer to:
Office Space is a 1999 American comedy film written and directed by Mike Judge. It satirizes the everyday work life of a typical mid-to-late-1990s software company, focusing on a handful of individuals fed up with their jobs.
An officer is a member of an armed forces or uniformed service who holds a position of authority.
Office 365 is a line of subscription services offered by Microsoft as part of the Microsoft Office product line.
Offal (), also called variety meats, pluck or organ meats, is the viscera (internal organs) and entrails of a butchered animal.
An Offshore Financial Centre or OFC is defined as a country or jurisdiction that provides financial services to nonresidents on a scale that is incommensurate with the size and the financing of its domestic economy.
The Office of Strategic Services (OSS) was a wartime intelligence agency of the United States during World War II, and a predecessor to the Central Intelligence Agency (CIA).