OF or Of may refer to:
Office 365 is a line of subscription services offered by Microsoft, as part of the Microsoft Office product line.
An officer is a member of an armed force or uniformed service who holds a position of authority.
In American football, an official is a person who has responsibility in enforcing the rules and maintaining the order of the game.
An official state car is a car used by a government to transport its head of state or head of government in an official capacity, which may also be used occasionally to transport other members of the government or visiting dignitaries from other countries.
An Offshore Financial Centre or OFC is defined as a country or jurisdiction that provides financial services to nonresidents on a scale that is incommensurate with the size and the financing of its domestic economy.
Offal (), also called variety meats, pluck or organ meats, refers to the internal organs and entrails of a butchered animal.
Offset printing is a commonly used printing technique in which the inked image is transferred (or "offset") from a plate to a rubber blanket, then to the printing surface.
Of Mice and Men is a novella written by author John Steinbeck. Published in 1937, it tells the story of George Milton and Lennie Small, two displaced migrant ranch workers, who move from place to place in California in search of new job opportunities during the Great Depression in the United States.