SM or sm may refer to:
Smallpox was an infectious disease caused by either of two virus variants, Variola major and Variola minor.
Smallville is an American television series developed by writer-producers Alfred Gough and Miles Millar, based on the DC Comics character Superman created by Jerry Siegel and Joe Shuster.
A smartphone is a mobile personal computer with a mobile operating system with features useful for mobile or handheld use.
Short Message Service (SMS) is a text messaging service component of most telephone, World Wide Web, and mobile telephony systems.
A smart card, chip card, or integrated circuit card (ICC) is any pocket-sized card that has embedded integrated circuits.
Smoking is a practice in which a substance is burned and the resulting smoke breathed in to be tasted and absorbed into the bloodstream.