Zo or ZO may refer to:
Zoroastrianism, or more natively Mazdayasna, is one of the world's oldest extant religions, "combining a cosmogonic dualism and eschatological monotheism in a manner unique [...] among the major religions of the world".
Zolpidem, sold under the brand name Ambien among others, is a sedative primarily used for the treatment of trouble sleeping.
Zootopia is a 2016 American 3D computer-animated comedy film produced by Walt Disney Animation Studios and released by Walt Disney Pictures.
A zombie (Haitian French: zombi, Haitian Creole: zonbi) is a fictional undead being created through the reanimation of a human corpse.
Zooey Claire Deschanel (; born January 17, 1980) is an American actress, model and singer-songwriter. She made her film debut in Mumford (1999), followed by a supporting role in Cameron Crowe's film Almost Famous (2000).
Zoroaster (; from Greek Ζωροάστρης Zōroastrēs), also known as Zarathustra (; Avestan: 𐬀𐬭𐬙𐬱𐬎𐬚𐬀𐬭𐬀𐬰 Zaraθuštra), Zarathushtra Spitama or Ashu Zarathushtra, was an ancient Iranian-speaking prophet whose teachings and innovations on the religious traditions of ancient Iranian-speaking peoples developed into the religion of Zoroastrianism.