Zo or ZO may refer to:
Zoroastrianism, or more natively Mazdayasna, is one of the world's oldest extant religions, "combining a cosmogonic dualism and eschatological monotheism in a manner unique [...] among the major religions of the world".
Zootopia (known as Zootropolis in some regions) is a 2016 American 3D computer-animated buddy mystery comedy-adventure film produced by Walt Disney Animation Studios and released by Walt Disney Pictures.
A zombie (Haitian French: zombi, Haitian Creole: zonbi) is a fictional undead being created through the reanimation of a human corpse.
Zolpidem, sold as the brand name Ambien among others, is a sedative primarily used for the treatment of trouble sleeping.
The zodiac is an area of the sky centred upon the ecliptic, the apparent path of the Sun across the celestial sphere over the course of the year.
Zooey Claire Deschanel (; born January 17, 1980) is an American actress and singer-songwriter. She made her film debut in Mumford (1999), followed by her supporting role in Cameron Crowe's semi-autobiographical picture Almost Famous (2000).
A zoo (short for zoological garden or zoological park and also called an animal park or menagerie) is a facility in which animals are housed within enclosures, displayed to the public, and in which they may also breed.